It’s almost impossible to resist the urge to scratch that annoying itch.
But new research on mice reveals there’s much more happening under your skin than you might think when you give in.
Scratching activates the immune system

A new study shows that scratching triggers the body’s immune response by stimulating mast cells, which play a key role in allergic reactions.
Scratching leads to more inflammation

Mice that were allowed to scratch developed stronger inflammatory reactions in their skin compared to those prevented from scratching.
Protection against harmful bacteria

Researchers found that scratching reduced the presence of dangerous bacteria like Staphylococcus aureus on the skin, offering a surprising protective effect.
Scratching as an evolutionary advantage

Traditionally, scratching is thought to help remove parasites and harmful substances from the body – a key survival mechanism.
Itching can be both good and bad

While acute itching can boost immune protection, chronic itching linked to skin diseases can cause lasting damage.
Separate nerves control itch and inflammation

The study revealed distinct nerve pathways: some trigger the itch sensation, others intensify the inflammatory response.
Potential for new treatments

By targeting specific nerves, future treatments may block unpleasant itching while preserving beneficial immune responses.
Big focus on anti-itch medicine

Pharmaceutical companies and research groups are racing to find effective anti-itch treatments, highlighting a major medical need.
Itch is a complex phenomenon

Itching isn’t just one simple feeling; there are many types, making it challenging to find universal treatments.
Few effective remedies for itching

Currently, treatments mostly consist of numbing creams and sedative antihistamines, which often come with heavy side effects like drowsiness.
This article is based on information from Videnskab.dk.