Ibuprofen is a go-to remedy for pain and fever, found in medicine cabinets worldwide.
But behind its soothing effects are hidden dangers you probably never heard of. Here are some facts about the popular painkiller that might surprise you.
Ibuprofen can triple your risk of stroke

One of the most shocking revelations is that daily use of ibuprofen may triple the risk of having a stroke.
Some studies report an increased risk between 10 and 50 percent — and that’s within just a few weeks of use.
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Heart, liver and kidneys silently take a hit

Ibuprofen affects key organs in your body — especially the heart, liver and kidneys.
And you don’t need to use it long term to feel the effects: even short-term use at moderate doses can lead to serious damage.
It interacts with over 400 other drugs

Ibuprofen may interfere with the effectiveness of more than 400 other medications.
This is a critical risk, especially for those managing chronic conditions or taking prescription drugs regularly.
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Leftover pills can kill pets

A single dropped tablet can be fatal for cats or dogs. Ibuprofen is toxic to animals and can lead to severe organ damage or death, even in very small amounts.
It harms the environment

Ibuprofen doesn’t disappear when flushed away.
It ends up in rivers and lakes where it can damage aquatic life and disrupt plant ecosystems — an environmental issue few are aware of.
Men and women react differently

New research reveals that men and women metabolize ibuprofen differently.
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For example, the enzymes that process medicine behave in opposite ways depending on gender, which may cause drugs to stay longer in the male body.
It causes oxidative stress in the liver

Studies in mice found that ibuprofen increases the production of hydrogen peroxide in liver cells — a toxic compound that puts cells under stress and increases the risk of liver injury.
It disrupts your metabolism

In male mice, ibuprofen altered 34 different metabolic processes — including those responsible for breaking down vitamins, hormones and amino acids.
These changes raise concerns about how the drug impacts human biochemistry.
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Protein recycling is affected by gender

The proteasome, which breaks down damaged proteins in cells, reacted differently in male and female mice.
This suggests that the body’s cellular cleanup system may not work the same across sexes — with unknown consequences.
It should only be used short term

While ibuprofen is effective for pain, inflammation and fever, experts strongly recommend using it for the shortest time possible and in the lowest effective dose.
It’s far from harmless, especially with repeated or unnecessary use.
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This article is based on information from Scientias.nl.