Researchers have discovered that a simple and inexpensive supplement can improve memory in older adults in just three months.
In a twin trial, prebiotic fibers were combined with protein and light exercise with remarkable effects on brain function.
A twin study with strong control
The study included 36 pairs of older twins, where one received prebiotic fibers with protein, while the co-twin got a placebo.
This design made it possible to detect clear differences without background factors interfering with the results.
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Prebiotics feeding the brain’s helper bacteria
The prebiotic fibers consisted of inulin and fructooligosaccharides, which are not digested by the body but fermented by gut bacteria.
This led to a measurable increase in beneficial bacteria such as Bifidobacterium.
Improved performance on memory tests
After 12 weeks, participants in the prebiotic group scored higher on an overall cognitive factor and made fewer errors on the PAL test, which is especially sensitive to early Alzheimer’s-related changes.
A test that reveals the earliest changes
The PAL test measures the ability to connect patterns and locations.
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This specific function is among the first to decline in Alzheimer’s disease, making the improvement particularly meaningful.
No impact on muscle strength
Although all participants received protein powder and performed strength exercises, no difference was seen in muscle outcomes.
According to the researchers, physical improvements require more time than the 12 weeks of the study.
Well tolerated and high participation
Participants reported only mild and expected digestive discomfort.
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At the same time, adherence was high thanks to the fully remote design, which included online questionnaires, video calls, and mailed test kits.
Affordable and accessible solution
According to the researchers, prebiotic fibers are safe, inexpensive, and easily available.
This makes them an appealing option at a time when healthcare systems are under pressure and cost-effective solutions are in demand.
Why the brain responds before the body
Fiber fermentation produces signaling molecules and fatty acids that directly influence the brain through the nervous and immune systems.
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This may explain why memory improved quickly while muscle strength did not.
The aging microbiome plays a key role
As people age, the gut microbiome changes and the body becomes less effective at controlling inflammation.
Prebiotic fibers may help restore balance in the gut, which in turn benefits brain health.
Next steps in research
The scientists highlight the need for larger and longer trials to determine whether these memory improvements last and whether they translate into noticeable benefits in daily life for older adults.
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A step toward dementia prevention
While the study did not focus on people with dementia, the results suggest that simple dietary supplements may offer a promising way to support brain function and potentially prevent cognitive decline in the future.
This article is based on information from Earth.com.