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Combined abdominal obesity and muscle loss linked to 83% higher risk of death

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A long-term study of adults over 50 shows that the combination of abdominal fat and muscle loss is linked to an 83% higher risk of death, highlighting a largely overlooked health risk in ageing.

Many people notice subtle changes in their bodies as they age. Clothes fit differently, strength fades a little, and weight tends to settle around the waist.

These shifts are often dismissed as a normal part of getting older. But new research suggests that when certain changes occur together, they may signal something far more serious.

Scientists are increasingly focusing on the combination of muscle loss and abdominal fat, a pairing that may quietly raise the risk of early death in older adults.

When fat and muscle collide

Researchers from the Federal University of São Carlos in Brazil, working with University College London, followed more than 5,000 adults aged 50 and over for 12 years as part of the English Longitudinal Study of Ageing.

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Their analysis found that people with both excess abdominal fat and reduced muscle mass faced a dramatically higher risk of death than those without these traits.

This combination is known as sarcopenic obesity, a condition that blends age-related muscle loss with fat accumulation.

It is linked not only to mortality, but also to reduced independence, frailty, and poorer quality of life. The risk appears to come not from fat or muscle loss alone, but from the way the two conditions interact in the body.

Researchers explain that abdominal fat promotes chronic inflammation, which accelerates muscle breakdown.

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As fat infiltrates muscle tissue, it weakens strength, mobility, and metabolic function, creating a cycle that becomes increasingly difficult to reverse.

Simple measurements, earlier warnings

One of the most important findings of the study was that sarcopenic obesity does not require expensive scans to detect.

Instead of relying on MRI or CT imaging, the researchers demonstrated that simple clinical measurements can identify people at risk.

These include:

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  • waist circumference to assess abdominal obesity
  • basic calculations of lean muscle mass using age, height, weight, and sex

Using these accessible tools could allow earlier identification in routine healthcare settings, long before severe disability develops.

Why this matters for ageing populations

Interestingly, the study found that abdominal obesity alone did not increase mortality risk if muscle mass was preserved.

This highlights the protective role of muscle and underscores the importance of strength, not just weight, in healthy ageing.

The researchers argue that recognising sarcopenic obesity earlier could open the door to timely interventions, such as targeted exercise and nutritional support.

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As populations age worldwide, identifying this hidden risk factor may prove critical in reducing preventable deaths and preserving independence later in life.

Sources: Eurokalert and Springer Nature

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