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Eggplant seeds attract scientific interest in colon cancer research

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Early research suggests that compounds found in eggplant seeds may influence tumour growth in laboratory studies of colon cancer.

In most kitchens, seeds are an afterthought. They are scraped out, thrown away, and rarely considered part of the food itself.

But in medical research, those discarded parts are sometimes where the most interesting questions begin.

Researchers in southern Spain are now examining eggplant seeds as part of a broader effort to better understand how plant-based compounds may interact with cancer biology.

A research team led by the University of Granada, working with the Institute of Biosanitary Research and the Cellbitec Foundation, has studied extracts from the seeds of a specific eggplant variety.

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According to results published in the journal Food Bioscience, the extracts showed anti-tumour activity in laboratory experiments and animal models of colon cancer.

What the researchers examined

The scientists focused on mature, defatted eggplant seeds, analysing their chemical composition in detail.

They identified high levels of flavonoids and polyphenols, including well-known bioactive molecules such as kaempferol, quercetin and protodioscin.

These compounds have previously been linked to anti-inflammatory and anti-proliferative effects in cancer research.

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In experimental models, the seed extracts slowed the growth of tumour cells and interfered with cellular structures involved in cancer progression. Importantly, the researchers observed relatively low toxicity in healthy cells.

Why recurrence matters

Colon cancer often responds well to surgery and chemotherapy in its early stages, but recurrence remains a major challenge.

The Granada team reported that the eggplant seed extracts also affected cancer stem cells, which are frequently associated with treatment resistance and relapse.

Early findings, not a treatment

The researchers stress that their work is preliminary. Further molecular and pharmacological studies are needed to assess safety, dosing and potential clinical applications.

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The findings do not suggest a dietary treatment, but they do highlight how overlooked plant components may contribute to future complementary cancer research.

Sources: Infobae

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