The medication metformin is widely used to treat type 2 diabetes and as a preventive measure for at-risk patients.
According to health authorities such as the NHS, it is among the most commonly used drugs globally, with millions of patients receiving it each year.
The drug works by improving the body’s sensitivity to insulin and lowering blood sugar levels.
In some cases, it is also used to treat fertility problems caused by hormonal imbalances, including polycystic ovary syndrome (PCOS).
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Despite its widespread use, the treatment is not without side effects.
Nausea, diarrhea, and stomach pain are common, while long-term use may affect vitamin B12 levels, according to the NHS and Diabetes UK.
Limitations and risks
The treatment is not suitable for everyone. People with liver or kidney disease, severe infections, or heart problems should avoid metformin, according to NHS guidelines.
In rare cases, the drug may also cause serious reactions that require immediate medical attention.
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It is therefore emphasized that patients should always consult healthcare professionals before use.
In particular, it may be necessary to temporarily stop treatment in connection with surgery or certain scans.
Exercise and cancer
Researchers from the University of Miami Miller School of Medicine have examined the effects of metformin in patients with prostate cancer in a study published in EMBO Molecular Medicine.
The study shows that the drug increases the levels of a molecule associated with energy balance and weight regulation.
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According to the researchers, this effect mimics some of the biological processes that normally occur during physical activity.
This is particularly relevant for cancer patients, who often have limited ability to exercise during treatment.
The findings therefore suggest that metformin may help support the body’s metabolism in situations where physical activity is difficult.
However, the researchers emphasize that the medication cannot replace exercise, but may serve as a supplement to treatment.
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Sources: LADbible, NHS, Diabetes UK, and EMBO Molecular Medicine.
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