Long-term acid reflux can damage the lining of the esophagus.
According to UCF College of Medicine, as cited by News-Medical, this may lead to inflammation and damage to the cells' genetic material.
Over time, some patients may develop Barrett's esophagus, a condition that increases the risk of esophageal cancer.
The American Cancer Society reports that approximately 22 percent of patients with esophageal cancer survive for five years after diagnosis.
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Focus on bacteria
Researchers at UCF College of Medicine are now investigating the role that bacteria in the esophagus play in the development of the disease.
When stomach acid and bile salts affect the esophagus over an extended period, beneficial bacteria may struggle to survive.
According to the researchers, this creates an opportunity for other bacteria that may contribute to increased irritation and tissue damage.
Promising results
The researchers are working with the bacterial group Lactobacillus spp., which is commonly found in probiotic products.
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According to UCF College of Medicine, early results suggest that these bacteria may improve the environment in the esophagus and reduce the development of Barrett's esophagus.
In the models studied, cancer also developed later than in those that did not receive the probiotic treatment.
As a result, researchers are now investigating whether a simple probiotic treatment could eventually help both relieve acid reflux and prevent esophageal cancer.
Sources: News-Medical, UCF College of Medicine, and American Cancer Society.
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This article is made and published by Ida-Marie Palm Varbæk, who may have used AI in the preparation.