Scientists explain why alcohol can leave you feeling anxious the next day

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That uneasy feeling after a night of drinking isn't just in your head. Research reveals why it happens and why some people are more affected than others.

You probably know the feeling. You wake up a few hours after a night out, and before you have even opened your eyes, a wave of worry rolls in. Nothing in particular is wrong, yet everything feels wrong.

That morning dread has a name. "Hang-xiety" is the anxiety that often comes with a hangover, and researchers have spent the last few years mapping out why some people get hit by it and others barely notice.

Why your brain rebounds the morning after

Alcohol works on two of the brain's main chemical messengers. It boosts GABA, which calms nerve-cell activity, and it dampens glutamate, which does the opposite. That is why a drink can feel like the volume knob on your worries has been turned down.

The problem is the rebound. As the alcohol clears, GABA activity drops and glutamate activity bounces back, leaving the brain in an over-alert state the morning after.

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Your body also treats alcohol as a stressor. A review in Alcohol Research: Current Reviews, the journal of the US National Institute on Alcohol Abuse and Alcoholism, describes how acute drinking activates the hormonal system that releases cortisol.

In social drinkers, cortisol usually rises during a session, especially at higher blood alcohol levels. Add in a broken night of sleep and dehydration, and you have a nervous system primed to find threats where there are none.

These drinkers may feel it the hardest

A 2019 study in Personality and Individual Differences by researchers at the University of Exeter followed 97 social drinkers at home, randomly assigned to drink as usual or stay sober.

Highly shy people felt slightly less anxious during the evening they drank. The next morning, that calm was gone, and their anxiety had climbed well above where it started.

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The team also found that stronger hang-xiety in shy drinkers tracked with higher scores on a questionnaire used to screen for alcohol use disorder. That hints the morning rebound may play a role in how drinking problems take hold.

A larger 2023 study published in the Journal of Clinical Medicine followed more than 5,000 university students in the United Kingdom and the Netherlands.

People who described themselves as hangover-sensitive reported higher anxiety and stress during a hangover than hangover-resistant drinkers. The gap was small on average, but the pattern held.

What tends to help

The most direct way to avoid hang-xiety is to drink less, or not at all. Water alongside alcohol, food before and during a session, and a slower pace all take the edge off.

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Sleep matters too. Alcohol disrupts the deeper, rapid-eye-movement sleep that helps the brain regulate emotion, so an early night does not always deliver real recovery.

Anyone who finds that worry or low mood after drinking is starting to shape how they live, or who leans on alcohol to get through social situations, should bring it up with a doctor. Needing a drink to feel at ease is a warning sign the Exeter researchers flagged in their work.

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This article is made and published by Ida-Marie Palm Varbæk, who may have used AI in the preparation.

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