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Birth control pills may affect mental health more than previously recognised

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New research reveals that hormonal birth control may affect mental wellbeing differently depending on a woman’s genetic makeup.

Most women remember the moment they reached for their first pack of birth control pills — not just as a form of contraception, but as a step toward independence.

For many, it marked the beginning of choices, plans and possibilities. But as more research unfolds, it becomes clearer that the story of the pill is more nuanced than we once believed.

A closer look at how contraception shapes wellbeing

A new study from the University of Copenhagen suggests that access to birth control pills during adolescence may have long-term effects on mental health for some women.

Led by researcher Franziska Valder, the team examined large U.S. datasets combining women’s life histories, genetic risk markers and state laws governing teen access to contraception.

Also read: GLP-1 therapies included in WHO’s recommendations for the first time

The findings indicate that women with a high genetic predisposition for depression showed significantly poorer mental wellbeing later in life if they had access to the pill during their teenage years.

While the pill empowered generations, the researchers argue that its impact on mental health has been insufficiently explored.

When genes and hormones collide

Rather than blaming the pill itself, the researchers point toward an interaction: a genetic vulnerability that may be triggered by hormonal contraception.

This group of women showed reduced education years, lower job productivity and more sick days compared with peers not exposed to early access.

Also read: Diet shift helped one woman cut her cholesterol by 15 percent

The study doesn’t claim that all women face these effects — only a specific subset. But for those affected, the consequences appear meaningful enough to reconsider how hormonal contraception is prescribed and monitored.

A call for more tailored contraceptive choices

The authors emphasize that the pill remains an important and effective contraceptive method. Their message is not to discourage its use, but to recognise that it may not be equally suitable for everyone.

The study highlights two needs moving forward:
• better screening for women with potential mental health risks
• stronger investment in non-hormonal contraceptive alternatives

With global conversations on women’s health gaining momentum — and reproductive rights shifting dramatically in parts of the world — the findings come at a crucial moment.

Also read: Study identifies cellular process that could change cholesterol treatment

Understanding how contraception affects bodies and minds is essential to ensuring informed choices for future generations.

The article is based in information from Ritzau

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