Popular injections like Ozempic and Mounjaro have dominated headlines in the weight-loss world. But new U.S. research shows that bariatric surgery leads to dramatically better and longer-lasting weight loss. Here are the study’s key takeaways.
Bariatric Surgery Leads to Major Weight Loss

Patients undergoing surgery lost an average of 26.3 kilograms over two years—far more than those using medication.
Ozempic Users Lose Less Than Expected

Those who used GLP-1 medications like Ozempic for six months lost just 5.4 kilograms on average.
Over 51,000 Patients Were Studied

The study, conducted by NYU Langone Health and NYC Health + Hospitals, analyzed data from more than 51,000 individuals.
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Real-World Results vs. Clinical Trials

Previous clinical trials showed weight loss of 15–21% with GLP-1 drugs. In practice, the real-world effect was closer to 4.7%.
Surgery Yields 24% Total Body Weight Loss

Patients who had bariatric surgery saw a 24% reduction in body weight—five times more than with GLP-1 drugs.
High Dropout Rate Among Medication Users

Roughly 70% of patients stopped taking GLP-1 drugs within the first year. After two years, 72% had discontinued use.
GLP-1 Drugs Are Widely Used, But Surgery Is Rare

While 12% of Americans have tried GLP-1 medications, only 1% of those eligible for surgery actually undergo the procedure.
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Surgery Seen as More Sustainable

Researchers believe surgical options offer more durable results and better long-term outcomes for those struggling with obesity.
Experts Urge Realistic Expectations

The study’s authors recommend that patients manage expectations for medication-based treatments or consider surgical alternatives.
Drug Companies Decline to Comment

Despite the study’s impact, major pharmaceutical companies like Novo Nordisk and Eli Lilly have not responded publicly.
This article is based on information from Fox News
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