Alzheimer’s disease affects millions of people globally, but new research reveals that everyday habits like prolonged sitting might quietly raise your risk. A study led by Vanderbilt University Medical Center and the University of Pittsburgh uncovers why staying active throughout the day could be crucial for protecting your brain health as you age.
Sedentary Behavior Linked to Brain Shrinkage
The research revealed that older adults who spent more hours sitting or lying down experienced noticeable brain shrinkage in regions tied to Alzheimer’s risk.
Cognitive Decline Occurred Regardless of Exercise
Surprisingly, the damage associated with long periods of sitting was present even in participants who engaged in regular exercise routines.
Seven-Year Study Spanning Over 400 Adults
The study followed 404 adults aged 50 and older over seven years, combining brain imaging, cognitive testing, and activity tracking.
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Continuous Activity Monitoring Used
Participants wore wrist devices for a week to objectively measure their daily movements and sedentary behavior, ensuring precise data collection.
Genetic Risk Intensified the Effect
Individuals carrying the APOE-e4 gene — a known genetic risk factor for Alzheimer’s — showed even stronger links between sitting and cognitive decline.
Exercise Alone Is Not Enough
The study emphasized that reducing sedentary time, not just focusing on daily exercise sessions, plays a vital role in maintaining brain health.
Breaks From Sitting Are Crucial
The researchers recommend that adults make it a priority to take frequent breaks from sitting throughout the day, aiming to break up long sitting periods.
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Lifestyle Habits Influence Brain Health
This research underscores the critical role lifestyle choices play in brain aging, supporting the notion that small, consistent behavior changes can have a big impact.
A Call for Movement in Older Adults
Older adults, especially those at genetic risk for Alzheimer’s, may benefit from integrating more movement into their daily routines, such as walking, stretching, or light activity.
Supported by Leading Health Organizations
The study was backed by the Alzheimer’s Association and the National Institute on Aging, highlighting the scientific community’s focus on prevention strategies that go beyond medications.
This article is based on information from News Medical
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