Alzheimer’s disease is one of the most feared conditions of old age, and researchers worldwide are racing to uncover what might protect the brain. A new study from London points to a particular type of fat in our diet – and surprisingly, the effect seems to matter only for women.
Omega-3 appears to shield the brain
Researchers found that women diagnosed with Alzheimer’s had significantly lower levels of omega-3 fatty acids in their blood compared to healthy women of the same age.
No similar trend in men
Among men, the scientists observed no meaningful difference in omega-3 levels between healthy participants and those with mild cognitive impairment or Alzheimer’s.
Study included 841 participants
Blood samples were taken from both healthy individuals, patients with mild cognitive decline, and those formally diagnosed with Alzheimer’s, giving the researchers a wide pool of data to analyze.
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700 lipids examined in detail
The scientists screened for around 700 types of lipids, the fat molecules that play crucial roles in inflammation, brain structure, and nerve function.
Higher levels of saturated fats in women
Women with Alzheimer’s also had a noticeable increase in saturated fats – often referred to as “unhealthy fats” – compared with women without the disease.
Statistical evidence of a link
The results suggest a possible causal relationship between fatty acid balance in the blood and the risk of developing Alzheimer’s, though this has not yet been proven.
Research highlights sex-specific differences
The fact that the effect was observed only in women could open new avenues in understanding why Alzheimer’s affects women disproportionately after the age of 80.
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Omega-3 sources in the diet
Fatty fish such as salmon, herring, and mackerel are among the best natural sources of omega-3, though supplements may be a useful option for those who rarely eat fish.
Clinical trials are the next step
The researchers stress that more work is needed before firm conclusions can be drawn. Controlled clinical studies will be essential to determine whether adjusting lipid intake can truly alter the course of Alzheimer’s.
Women’s brain health under the spotlight
Since women are diagnosed with Alzheimer’s more often than men, focusing on dietary habits and ensuring sufficient omega-3 intake could prove vital in future prevention strategies.
This article is based on information from Videnskab.dk
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