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Study finds 49% lower dementia risk with higher vitamin B intake

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A long-term Japanese study suggests that eating more vitamin B2 could nearly halve the risk of developing disabling dementia

We all have those moments — walking into a room and forgetting why, losing our train of thought mid-sentence, or blanking on a familiar name.

Most of the time, it’s harmless. Still, many quietly wonder what they can do now to protect their brain as they age.

While there’s no magic fix, new research suggests that some simple changes at the dinner table could make a measurable difference.

A 15-year look at diet and dementia

Researchers from Japan’s Circulatory Risk in Communities Study (CIRCS) followed over 4,000 adults between 40 and 69 years old for more than 15 years.

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Their goal was to see how different B vitamins might relate to long-term brain health. Using detailed dietary records — not supplements — scientists compared participants who consumed the least B vitamins with those who consumed the most.

Published in the European Journal of Clinical Nutrition, the study found that higher intakes of riboflavin (vitamin B2) were associated with a 49% lower risk of developing disabling dementia.

People who consumed more vitamin B6 and folate also had a modestly reduced risk, while vitamin B12 didn’t appear to play a significant role.

What the results mean

Although the study cannot prove direct cause and effect, the findings support the idea that B vitamins — especially riboflavin — may protect the brain by supporting energy metabolism and maintaining healthy blood vessels.

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These nutrients help manage homocysteine, an amino acid linked to cardiovascular and cognitive decline when levels are too high.

Scientists note that the association was strongest among participants without a history of stroke, hinting that riboflavin and B6 could be particularly relevant for nonvascular forms of dementia.

Still, they emphasize that no single nutrient prevents disease on its own — it’s the broader pattern of eating that matters.

Everyday ways to boost your B vitamin intake

If you’d rather improve your diet than reach for supplements, it’s easier than it sounds. B2, B6 and folate appear naturally in many everyday foods, including:

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  • Riboflavin (B2): milk, yogurt, eggs, lean meats, fish, mushrooms, almonds, spinach
  • Vitamin B6: chicken, salmon, chickpeas, potatoes, bananas, squash
  • Folate: leafy greens, beans, lentils, citrus fruit, and fortified grains

A balanced approach — think lentil salads with greens, eggs for breakfast, or yogurt with almonds as a snack — provides these vitamins along with fiber, minerals, and healthy fats that benefit the brain.

The bigger picture

Experts from the National Institutes of Health and other research institutions agree that food-based nutrients are generally more effective than supplements for long-term health.

While popping a pill may seem easier, the body absorbs vitamins differently when they come from real food — often alongside other compounds that enhance their effect.

Article based on information from the European Journal of Clinical Nutrition

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