In your early twenties, life usually feels open and fast-moving. Plans revolve around careers, friendships, and the future, not medical tests or neurological terms most people associate with old age.
That sense of distance from serious illness is something many young adults take for granted, until it suddenly disappears.
That was the reality faced by a family in Norfolk after subtle changes in a young man’s behaviour led to a diagnosis that doctors rarely see in someone so young.
A diagnosis no one expected
Andre Yarham was 22 when specialists confirmed he had frontotemporal dementia, a rare and aggressive form of the disease.
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He was believed to be the youngest diagnosed dementia patient in the UK. Brain scans showed damage more typical of someone decades older, surprising clinicians involved in his care.
Andre lived in Dereham and had been healthy before symptoms began appearing in 2022. Over time, doctors linked his condition to abnormal protein changes in the brain, a known cause of frontotemporal dementia.
According to the NHS, this form of dementia often affects personality, language, and decision-making rather than memory alone.
Andre died over the Christmas period aged 24. His family said he donated his brain to science, hoping his case could support future research into early-onset dementia.
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Subtle warning signs
The first changes were easy to miss. Family members noticed increasing forgetfulness, difficulty focusing, and moments where Andre seemed mentally absent. Within a year, scans confirmed early-onset dementia.
NHS England lists early dementia symptoms as including:
- memory and concentration problems
- confusion about time or place
- difficulty finding words
- emotional or behavioural changes
Only around 0.1 percent of people in the UK develop dementia before 65, making cases like Andre’s extremely rare.
Why his case matters
There is currently no cure for frontotemporal dementia and no treatment proven to slow its progression. Care focuses on managing symptoms and providing support.
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Researchers say rare cases in young adults are crucial for understanding genetic and biological triggers.
Andre’s donation may help scientists identify patterns that could lead to earlier diagnosis or future treatments.
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