According to HealthDigest, the change in Oprah Winfrey’s weight began in 2023, when she started taking a medication from the GLP-1 group, which is also used in drugs such as Ozempic.
This type of medication has, in recent years, been discussed both positively and negatively, and several well-known figures have said they use it in connection with weight loss.
Doctors discuss the treatment
The use of GLP-1 medication among older adults is still being debated among doctors.
In an analysis by the American Academy of Medical Colleges, specialists note that the treatment requires special attention for patients over the age of 65.
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Physician Chitra Ganta explains in the analysis that many older adults live with severe obesity. Therefore, in some cases, the medication can help improve health.
Researcher John Batsis has previously been critical of the treatment for older adults. Today, he believes the medication can be used if treatment begins with a low dose that is increased slowly.
This is how much Oprah weighs now
Oprah Winfrey has also spoken about her own experiences with the treatment. On the television program TODAY, she explained that she experienced constipation as a side effect.
She also said that she drinks a lot of water and takes magnesium to reduce the problem.
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In an interview with CBS News in 2025, Oprah Winfrey said that her weight was around 155 pounds.
The information emerged during a conversation with journalist Jane Pauley.
In the podcast Wild Card with Rachel Martin, Winfrey also said that the medication itself does not prevent weight gain.
When she stopped the treatment, she gained about 20 pounds again, corresponding to 9 kilograms.
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In the end, she chose to start the medication again, and the treatment has become a permanent part of her lifestyle.
Sources: HealthDigest, American Academy of Medical Colleges, TODAY, CBS News, and Wild Card with Rachel Martin.
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