A plant compound may protect skin cells from UV damage and lower skin cancer risk

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The source is a tropical tree, the mechanism is double, and researchers think it could one day complement an ordinary sunscreen.

You probably have a bottle of sunscreen somewhere in the bathroom. For most of us, it comes out in summer and then disappears for the rest of the year. The compounds that make it work are almost always made in a lab.

A new study points to a possible natural alternative. Researchers in Brazil tested a plant alkaloid called brachycerine, taken from the leaves of a tropical tree, and found it shielded human skin samples from damage caused by UV-A and UV-B light.

The work appeared on November 4, 2026 in the journal Photochemistry and Photobiology. The team is based at the Federal University of Rio Grande do Sul in Brazil.

How the plant alkaloid blocked UV damage

Brachycerine is produced naturally in a small tree called Psychotria brachyceras. In the plant, it absorbs ultraviolet light and mops up damaging chemicals called free radicals. That dual role is what caught the researchers' attention.

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When they added brachycerine, or an extract from the leaves, to formulations applied to human skin samples, the compound did two things at once. It blocked UV before the energy could reach the deeper layers.

It also neutralized the harmful byproducts that UV radiation creates inside cells.

According to the researchers, the alkaloid has a dual mode of action. It shields skin from UV and neutralizes the destructive chemicals that the same radiation produces in cells.

This is still early-stage research. The tests were done on human skin samples in the lab, not on living people wearing the product.

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The compound was also not toxic to the mammalian cells the team worked with. That is a basic safety signal, but a long way from full clinical testing.

Why natural sun protection matters now

Skin cancer is the most common cancer in the United States. The American Academy of Dermatology estimates that one in five Americans will develop skin cancer in their lifetime, and that roughly 9,500 people are diagnosed with it every day.

Most of those cancers trace back to ultraviolet exposure. The majority of melanoma cases, the most dangerous form, are attributed to UV light.

Standard advice from dermatologists is to use a broad-spectrum sunscreen with SPF 30 or higher, to seek shade, and to wear protective clothing.

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Brachycerine does not replace any of that. The authors position it as a possible addition to existing sunscreen formulations, not a substitute. The source plant can be grown from cuttings, which the team sees as a practical advantage for large-scale production.

The next step is clinical testing on volunteers, which has not yet taken place.

Also read: One cup of oatmeal a day: what it actually does to your cholesterol

This article is made and published by Mie Hermansen, who may have used AI in the preparation.

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