Depression affects millions worldwide, but new research highlights three unexpected factors that could lower the risk.
From diabetes medication to simple lifestyle changes, here’s what scientists have discovered.
Ozempic and similar drugs may reduce depression

A recent study found that people taking GLP-1 medications like Ozempic for diabetes had a 10% lower risk of depression compared to those using other diabetes treatments.
Not all diabetes medications have the same effect

Researchers discovered that GLP-1 drugs were more effective in reducing depression risk than DPP4i medications like Januvia, suggesting that certain diabetes treatments may have mental health benefits.
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The link between weight loss and mood

Experts believe that the reduced risk of depression may be linked to weight loss, improved blood sugar control, and an overall sense of better health.
Daily intake of citrus may lower depression risk

A study found that consuming one medium orange per day could reduce the risk of depression by up to 20%, possibly due to its positive effects on gut microbiota.
Citrus fruits boost beneficial gut bacteria

Scientists observed that citrus fruits increased specific gut bacteria associated with better mental health, an effect not seen with other fruits.
Regular exercise protects the brain

A large study involving over 73,000 participants, set to be presented in April 2025, revealed that moderate to intense physical activity reduces the risk of depression and other neurological disorders.
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Lower risk of mental health disorders

Participants who engaged in more exercise had up to a 40% lower risk of developing depression, anxiety, dementia, and sleep disorders compared to inactive individuals.
You can control your activity level

Unlike genetic factors, physical activity is something individuals can change, meaning an active lifestyle could potentially help prevent depression.
A healthy lifestyle may prevent depression

Findings suggest that small daily changes – such as adjustments in diet, medication, and exercise – can have a significant impact on mental well-being.
Experts encourage lifestyle changes

Researchers emphasize the need for a stronger focus on prevention through diet and exercise to help reduce the global burden of depression.
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This article is based on information from Medical News Today.
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