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New research reveals vitamin D3 may protect the heart after attack

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New research shows that tailoring vitamin D3 levels after a heart attack could cut the risk of another in half — a small change with big potential for heart health.

Heart disease remains one of the world’s biggest killers — yet for millions recovering from a heart attack, the focus often turns to lifestyle, medication, and stress management.

But what if a simple nutrient, one that most people already have in their kitchen cabinet, could quietly help protect the heart from another attack?

That’s what a team of researchers in Utah set out to explore, and their results have surprised even experienced cardiologists.

A different approach to recovery

Scientists from Intermountain Health in Salt Lake City have discovered that carefully adjusting levels of vitamin D3 — rather than just taking a standard daily dose — may dramatically lower the risk of a second heart attack.

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The study, known as the TARGET-D trial, followed more than 600 people who had recently experienced a heart attack.

Instead of prescribing the same supplement to everyone, doctors measured each patient’s blood levels and tailored the dose until it reached an optimal range.

After several years of monitoring, patients whose vitamin D3 levels were managed through this personalized method were found to have half the risk of another heart attack compared with those who received no targeted treatment.

From sunlight to science

For decades, vitamin D has been associated with bone health and immunity, but researchers have increasingly linked low levels to heart disease and inflammation.

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With modern lifestyles limiting sun exposure — once the main natural source of vitamin D — deficiency has become widespread.

In this new study, most participants began with levels below 40 nanograms per milliliter, a threshold considered insufficient.

Through regular testing and dose adjustments, many required 5,000 international units (IU) daily — far more than standard recommendations — to reach healthy levels.

While earlier trials failed to find a clear connection between vitamin D and reduced cardiac events, they rarely checked whether patients’ blood levels ever became optimal.

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Intermountain Health’s research fills that gap by treating supplementation as a measurable, precision-based therapy rather than a one-size-fits-all vitamin.

Why it matters

The potential impact could be significant. Roughly half of the global population has low vitamin D levels, according to epidemiological data, meaning a tailored approach might help millions lower their cardiovascular risk.

Researchers plan to expand the study to determine whether this strategy could also reduce strokes, heart failure, or other complications.

They emphasize that vitamin D3 management is not a replacement for medical therapy but could be a complementary tool for long-term heart protection.

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If future trials confirm these results, personalized vitamin D monitoring may become a routine part of cardiac aftercare — a small adjustment with potentially life-saving results.

The article is based on information from ScienceDaily

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