Home Blog Page 96

How covid-19 develops day by day throughout the course of the illness

Covid-19 can develop differently from person to person. Symptoms usually appear a few days after infection and can vary in both order and severity.

Here is an overview of how the illness typically progresses.

Symptoms appear after a few days

Photo: Shutterstock.com

Symptoms of covid-19 typically occur between 2 and 14 days after contact with the virus. For many, they begin around 5 to 6 days after infection.

Most people experience mild to moderate symptoms

Photo: Shutterstock.com

In the initial phase, the vast majority experience mild to moderate symptoms, which can last up to two weeks.

The first sign

Photo: Shutterstock.com

According to research, fever is the symptom that most frequently appears first. This differs from influenza, where cough more often serves as the initial symptom.

Fever is very common

Photo: Shutterstock.com

A review published in PLOS One of data from nearly 25,000 adults showed that about 78 percent of people with covid-19 had a fever.

Additional symptoms may develop in the second week

Photo: Shutterstock.com

After the first few days, the illness may progress with cough, sore throat, muscle aches, and headache.

Nausea and vomiting may occur early

Photo: Shutterstock.com

Statistical models suggest that nausea and vomiting can occur earlier in the course of covid-19 than in similar respiratory infections such as MERS and SARS.

Severe cases may require hospitalization

Photo: Shutterstock.com

In severe cases, the illness can lead to Acute Respiratory Distress Syndrome, in which the lungs do not supply enough oxygen to the body.

Some patients require intensive care treatment around 10 days after the first symptoms appear.

Symptoms vary from person to person

Photo: Shutterstock.com

The order and type of symptoms are not the same for everyone. Some may experience gastrointestinal problems before fever or cough, while others may have no symptoms at all.

Additional common symptoms

Photo: Shutterstock.com

In addition to the most well-known signs, the illness can also cause chills, fatigue, loss of taste or smell, and nasal congestion.

Signs of severe illness

Photo: Shutterstock.com

Shortness of breath, confusion, chest pressure, and difficulty moving or speaking are serious symptoms that require immediate medical attention.

Different variants cause similar symptoms

Photo: Shutterstock.com

Variants such as Omicron, Alpha, Beta, Gamma, and Delta generally cause the same symptoms. However, some data suggest that Delta may more closely resemble a common cold, with headache, runny nose, and sore throat.

The duration of the illness can vary

Photo: Shutterstock.com

For most people, covid-19 lasts from a few days to a few weeks. However, some experience symptoms that continue for a longer period.

Long-term symptoms may occur

Photo: Shutterstock.com

Long-term effects refer to symptoms that last for several weeks or months after the infection.

According to the CDC, symptoms are considered long-term if they persist for 4 weeks or more.

How long are you contagious?

Photo: Shutterstock.com

Most people can be around others again about 10 days after symptom onset or 10 days after a positive test.

People with severe symptoms or weakened immune systems may need up to 20 days of isolation.

Covid-19 and influenza are similar

Photo: Shutterstock.com

Both illnesses are respiratory diseases with similar symptoms.

However, research indicates that cough is more often the first symptom of influenza, while fever typically appears first in covid-19. Loss of taste and smell is also more common with covid-19.

When to contact a doctor

Photo: Shutterstock.com

With mild to moderate symptoms, emergency treatment is not always necessary.

However, medical attention should be sought in cases of breathing difficulties, chest pain or pressure, confusion, difficulty staying awake, or discoloration of the skin, lips, or nails.

The illness usually resolves on its own

Photo: Shutterstock.com

Covid-19 typically clears within 14 days. Rest, plenty of fluids, and over-the-counter pain relievers can help ease symptoms.

Sources: Medical News Today, PLOS One, and CDC.

Spain introduces new drug for rare genetic form of ALS

Spain has begun using a new therapy that may bring cautious optimism to a small group of people living with amyotrophic lateral sclerosis.

The disease, better known as ALS, progresses quickly and affects the nerve cells that control voluntary movement.

For years, treatment options have been limited and mostly focused on slowing symptoms.

Now doctors in Catalonia have started administering a drug that researchers believe could change how a specific genetic form of ALS develops.

A new medical step

At the Germans Trias i Pujol University Hospital in Spain, specialists have started treatment with a drug called Tofersen.

The therapy has been given to a 44-year-old patient diagnosed with ALS linked to a mutation in the SOD1 gene.

This genetic variation accounts for roughly 2 percent of ALS cases and is among the most common inherited forms of the disease.

The European Medicines Agency approved compassionate use of the drug in 2024, and Spain’s Ministry of Health recently authorised and funded its use in the public healthcare system.

What research shows

International clinical studies suggest the drug may help slow the functional decline experienced by patients with SOD1-related ALS.

Researchers observed that some patients maintained breathing capacity and muscle strength longer than expected.

In extension phases of the trials, about a quarter of participants showed early improvement in clinical measurements of daily function.

Tofersen works by targeting the genetic mutation believed to drive the disease process in this subgroup of patients.

How the treatment works

The medication is delivered through injections into the spinal fluid. The first stage involves three doses given every two weeks, followed by monthly treatments.

The therapy requires coordination between neurologists, anesthesiologists and hospital pharmacy teams.

ALS remains one of the most aggressive neurodegenerative diseases. It gradually destroys motor neurons in the brain and spinal cord, leading to muscle weakness, paralysis and eventually respiratory failure.

Sources: Infobae

Scientists report breakthrough approach in preclinical Alzheimer’s study

Watching a loved one slowly lose memories is one of the most painful experiences many families face.

Despite decades of research, effective treatments for Alzheimer’s disease remain limited.

Now, a new animal study is offering a different angle that is turning heads in the scientific community.

Researchers from the Institute for Bioengineering of Catalonia (IBEC) and West China Hospital of Sichuan University report that they reversed key signs of Alzheimer’s in mice using just three injections of specially engineered nanoparticles.

Instead of targeting brain cells directly, the team focused on repairing the brain’s vascular system.

A shift in strategy

Most Alzheimer’s therapies aim at neurons. This study, however, targeted the blood-brain barrier, the protective network of blood vessels that regulates what enters and leaves the brain.

When this barrier malfunctions, toxic proteins such as beta-amyloid accumulate. The scientists designed supramolecular nanoparticles to restore the barrier’s natural cleaning function and help remove these harmful proteins more efficiently.

What happened in mice

The team tested the therapy on genetically modified mice that develop memory loss similar to Alzheimer’s.

After three doses, researchers observed:

  • A sharp reduction in beta-amyloid buildup
  • Noticeable improvements in memory performance
  • Long-lasting effects months after treatment

According to reporting by La Vanguardia, the improvements were significant in animal models

Source: Clarin

Your mouth and gut may determine how severe your peanut allergy becomes, new research shows

Research indicates that bacteria in the mouth and intestines may influence how strongly the body reacts to peanuts.

This emerges from a study published in the journal Cell Host & Microbe, led by researchers from McMaster University.

The researchers investigated why individuals with the same type of allergy antibodies can react very differently.

Some develop severe symptoms, while others can tolerate small amounts of peanuts without a noticeable reaction.

According to the study, part of the explanation may be the body’s microbiome. This refers to the many bacteria that naturally live in places such as the mouth and digestive system.

Experiments with saliva and intestinal samples

In the study, the researchers analyzed saliva samples and samples from the upper part of the intestine from healthy participants.

They identified several bacteria capable of breaking down proteins from peanuts that can otherwise trigger allergic reactions.

A group of bacteria called Rothia proved to be particularly interesting.

The researchers write in the study that the bacterium can modify peanut proteins so that they activate the immune system’s antibodies to a lesser degree.

This process is central to the type of severe allergic reaction known as IgE-mediated anaphylaxis.

Link found in children

The results were also compared with data from 120 children.

The researchers found that children with higher levels of Rothia bacteria were generally able to tolerate larger amounts of peanuts before experiencing an allergic reaction.

In preclinical experiments, analyses also showed that the bacteria could reduce the amount of allergens reaching the bloodstream.

According to the researchers, the findings may, in the long term, contribute to new ways of predicting and treating food allergies, including through microbial treatments or improved immunotherapies.

Sources: Medical Xpress, and Cell Host & Microbe.

Living at high altitudes may reduce risk of type 2 diabetes, researchers find

Several observational studies have shown that the prevalence of type 2 diabetes is lower in regions located high above sea level.

The reason has long remained unclear, as lifestyle, genetics, and access to healthcare may all play a role.

However, a study published in Cell Metabolism offers a potential mechanism that could help explain the phenomenon.

Researchers from the Gladstone Institutes examined how low oxygen levels affect the body’s handling of glucose.

The findings suggest that red blood cells play a more active role in regulating blood sugar than previously assumed.

The hidden function of blood

Red blood cells are primarily known for transporting oxygen throughout the body. However, the study shows that under low-oxygen conditions, they absorb significantly more glucose from the bloodstream.

In experiments involving mice exposed to low oxygen levels comparable to conditions at high altitudes, blood sugar levels dropped rapidly.

At the same time, both the number of red blood cells and their ability to take up sugar increased.

The researchers describe how changes in the cells’ transport proteins and metabolism enable them to consume more glucose.

This challenges the traditional view of red blood cells as passive oxygen carriers.

A possible path to treatment

The research team also tested an experimental compound, HypoxyStat, which affects hemoglobin’s binding to oxygen and mimics the effect of low oxygen levels.

In diabetic mouse models, it led to the normalization of elevated blood sugar levels.

The findings open up new perspectives in diabetes treatment, which has so far focused primarily on insulin and muscle glucose uptake.

Mechanisms linked to oxygen levels and red blood cells could eventually serve as a complementary approach.

However, the researchers emphasize that the results are based on animal studies. It remains unclear how the effect will translate to humans, and clinical studies are necessary before the method can have practical significance.

Sources: Medical News Today, and Cell Metabolism.

Is cheese bad for your blood pressure? Here’s what research shows

New dietary guidelines published by the USDA maintain the recommendation of three daily servings of dairy products, which can include cheese.

But how does cheese actually affect blood pressure? Physicians specializing in cardiology and dietitians explain what happens both immediately and over time.

Cheese provides important nutrients

Photo: Shutterstock.com

Cheese contains calcium, potassium, and bioactive peptides, which are especially found in fermented dairy products.

Many people lack calcium

Photo: Shutterstock.com

A large portion of the population does not meet their calcium needs. Cheese can be one of the foods that helps increase intake.

Impact on blood pressure

Photo: Shutterstock.com

According to dietitian Jess Rybka, cheese generally has no immediate effect on blood pressure when consumed.

Limited knowledge about acute effects

Photo: Shutterstock.com

Joy Gelbman, a physician specializing in cardiology, explains that there is limited research on the short-term effects of cheese on blood pressure.

Daily intake showed no change in one study

Photo: Shutterstock.com

A randomized controlled study published in The American Journal of Clinical Nutrition found that six weeks of daily consumption of regular full-fat cheddar did not change daytime blood pressure compared with a dairy-free diet.

No difference between low-fat and full-fat cheese

Photo: Shutterstock.com

According to Joy Gelbman, several studies have found no difference in blood pressure between people who eat low-fat cheese and those who choose full-fat varieties.

Ultra-processed cheese is the exception

Photo: The Image Party / Shutterstock.com

However, all the experts point to one clear exception: ultra-processed cheese. This type can negatively affect blood pressure.

High salt content can raise blood pressure

Photo: Shutterstock.com

Ultra-processed cheeses often contain high levels of sodium. When consuming large amounts of sodium, the body draws water into the blood vessels to dilute it, increasing blood volume and thereby blood pressure.

Saturated fat also plays a role

Photo: Shutterstock.com

According to Randy Gould, a physician specializing in cardiology, research shows that a diet high in saturated fat can contribute to elevated blood pressure.

Therefore, the fat content of cheese is also worth paying attention to.

Choose cheeses with less sodium

Photo: Shutterstock.com

Randy Gould recommends choosing cheeses with lower salt content, such as Swiss cheese, fresh mozzarella, and ricotta.

Feta, Parmesan, blue cheese, and ultra-processed cheeses typically contain more sodium and should be eaten less frequently.

Balance your overall salt intake

Photo: Shutterstock.com

If you eat cheese daily, you should take the salt content into account and adjust your other food choices throughout the day.

Consider low-fat varieties if you have high cholesterol

Photo: Shutterstock.com

People with elevated cholesterol may benefit from choosing low-fat cheeses such as reduced-fat mozzarella, ricotta, or cottage cheese, as they contain less saturated fat and are less likely to increase LDL.

Use cheese as a flavor enhancer rather than the main ingredient

Photo: Shutterstock.com

Dietitian Abbey Sharp recommends viewing cheese as a supplement rather than the centerpiece of a meal. Finely grated or stronger cheeses can provide plenty of flavor in smaller amounts.

Combine with protein and vegetables

Photo: Shutterstock.com

For example, when making pizza, Sharp suggests cutting the amount of cheese in half and instead adding protein-rich grilled chicken and potassium-rich vegetables, as well as serving a salad on the side to increase satiety and fiber intake.

Eat potassium-rich foods with salty cheese

Photo: Shutterstock.com

If the cheese contains sodium, it may be beneficial to pair it with potassium-rich foods such as vegetables or beans to reduce its impact on blood pressure.

The key is to choose wisely

Photo: Shutterstock.com

If you want to protect your blood pressure, it is important to choose cheeses that are not ultra-processed and do not contain high levels of sodium or saturated fat.

In this way, cheese can remain part of your diet without placing strain on the heart.

Sources: Parade, USDA og The American Journal of Clinical Nutrition.

Almost seven million healthy life years lost to breast cancer due to these six lifestyle risks

According to an analysis published in The Lancet Oncology, the number of new breast cancer cases is expected to rise from 2.3 million in 2023 to more than 3.5 million in 2050.

This corresponds to an increase of approximately one third.

The figures are based on data from more than 200 countries collected between 1990 and 2023.

In the United Kingdom, around one in seven women will develop breast cancer during their lifetime, the study shows.

In 2023, three times as many new cases were recorded among women over the age of 55 as among women aged 20 to 54.

At the same time, the incidence among younger women has increased by 29 percent since 1990.

Health inequality

The study also shows that the disease burden is increasingly shifting to low- and middle-income countries.

In these countries, the disease is often detected later, and access to treatment may be limited.

Organizations such as Breast Cancer Now and Cancer Research UK emphasize, according to The Guardian, that prevention is important in reducing the number of cases.

Lifestyle plays a role

According to the analysis, a total of 6.8 million healthy life years were lost globally in 2023 as a result of breast cancer. Of these, 28 percent can be linked to six modifiable risk factors.

These include high consumption of red meat, smoking, elevated blood sugar, high BMI, alcohol consumption, and low levels of physical activity.

The largest contribution came from high consumption of red meat, which was associated with nearly 11 percent of the years of life lost.

Tobacco use accounted for 8 percent, while elevated blood sugar accounted for 6 percent.

Overall, the results indicate that more than a quarter of the disease burden could potentially be prevented through lifestyle changes.

Sources: The Guardian, and The Lancet Oncology.

White House explains rash seen on president Trump’s neck

The health of an American president has always drawn intense public attention. Even minor physical changes can spark debate, particularly in an era where every public appearance is photographed and shared instantly.

That scrutiny resurfaced this week after President Donald Trump appeared at the Medal of Honor Ceremony on 2 March with a visible scabbing rash on the right side of his neck.

Official response issued

As images circulated online, speculation quickly followed. In remarks provided by the White House, Trump’s personal physician, Sean Barbabella, said the president was applying a common topical cream as a preventative skin treatment.

According to the statement, the redness is expected to last several weeks. No further medical details were disclosed, and the White House did not indicate that the condition was linked to any broader health concern.

Past health disclosures

The incident has renewed focus on previous updates about Trump’s medical history. In July 2025, the White House confirmed he had been diagnosed with chronic venous insufficiency after experiencing leg swelling.

Officials said vascular testing, including Doppler ultrasounds, found the condition to be benign and common in people over 70.

Chronic venous insufficiency occurs when leg veins have difficulty returning blood to the heart, sometimes causing swelling or discomfort.

Earlier this year, Trump also addressed bruising on his hands in an interview with the Wall Street Journal, linking it to aspirin use. The White House has previously said frequent handshaking contributed.

The latest episode highlights the ongoing public interest in presidential health transparency.

Sources: LADbible

Three tablets may help accelerate the elimination of sleeping sickness

A committee of experts under the European Medicines Agency has recommended approval of the drug acoziborole for the treatment of sleeping sickness.

The recommendation is an important step before the medicine can be widely used, including in Congo, where most cases are found.

The treatment consists of three tablets taken at the same time. This marks a significant difference from previous therapies, which could last up to 10 days and required hospitalization.

In a 2023 study published in The Lancet Infectious Diseases involving around 200 patients in Congo and Guinea, more than 95 percent were considered cured 18 months after treatment, according to Powers Health.

The pharmaceutical company Sanofi has also pledged to donate the medicine to the World Health Organization so that patients can receive it free of charge.

A dangerous disease

Sleeping sickness, also known as African trypanosomiasis, is transmitted through bites from tsetse flies in sub-Saharan Africa, according to the CDC.

The disease often begins with symptoms resembling influenza. Later, the parasite can attack the brain.

This can lead to confusion, behavioral changes, and severe illness. Without treatment, it can be fatal.

Previous treatments have been both harsh and complicated. They often required spinal taps and hospitalization, posing a challenge in areas with limited access to hospitals.

Fewer infections

The number of cases has declined significantly in recent years. According to Powers Health, the figure fell below 10,000 in 2009 for the first time in 50 years.

In 2024, fewer than 600 cases of the most widespread type were recorded.

The World Health Organization aims to stop transmission by 2030. If the new pill works as hoped, it could become an important step toward that goal.

Sources: Powers Health, The Lancet Infectious diseases, and CDC.

How almonds can affect your body if you eat them every day

Almonds are a popular snack that is easy to take on the go and packed with nutrients.

According to nutrition experts, a daily handful of almonds can have several positive effects on the body.

Here are some of the things that may happen if you eat them every day.

Almonds are packed with nutrients

Photo: Shutterstock.com

Almonds are described as a nutrient-dense food because they contain plant-based protein, dietary fiber, healthy fats, and several vitamins and minerals.

The combination of these nutrients makes them a popular choice among nutrition experts.

They can help you feel fuller for longer

Photo: Shutterstock.com

The combination of protein, fiber, and healthy fats means that almonds can help keep you full for a longer period.

For this reason, they are often recommended as a snack that can help reduce snacking between meals.

A handful can be a suitable portion

Photo: Shutterstock.com

A commonly recommended portion is about 23 almonds or a generous handful. This amount is often used as a practical guideline for a snack.

Some studies use larger amounts

Photo: Shutterstock.com

Several recent studies have examined the effects of eating around two handfuls of almonds per day.

This corresponds to approximately 45 to 50 grams and can easily be spread across several snacks throughout the day.

Almonds contain several important nutrients

Photo: Shutterstock.com

A portion of roughly one handful provides calories, carbohydrates, fiber, fat, and protein.

In addition, almonds also provide minerals and vitamins such as magnesium, vitamin B2, and vitamin E.

The fat in almonds is the healthy type

Photo: Shutterstock.com

Although almonds contain fat, it is primarily unsaturated fatty acids. This type of fat is generally considered the more heart-friendly option.

They may support weight control

Photo: Shutterstock.com

Some people are concerned about the calorie content of nuts.

However, research published in Nutrients suggests that almonds may support weight management rather than make it harder to maintain a healthy weight.

Almonds are linked to lower cholesterol

Photo: Shutterstock.com

The study also found an association between almond consumption and lower cholesterol levels.

This is one of the reasons they are often mentioned as a heart-friendly snack.

They may influence blood pressure

Photo: Shutterstock.com

In addition to cholesterol, almonds were also associated with lower blood pressure in the study.

This is another factor that may contribute to improved cardiovascular health.

They may reduce the risk of heart disease

Photo: Shutterstock.com

Research also indicates that regular almond consumption is linked to a lower risk of heart disease.

This is partly due to their content of healthy fats and other beneficial nutrients.

Almonds may support gut bacteria

Photo: Shutterstock

Almonds contain fiber and polyphenols that serve as nourishment for beneficial bacteria in the gut.

This may help create a more diverse gut microbiome, according to a study published in the Journal of Applied Microbiology.

They may increase butyrate production

Photo: Shutterstock.com

According to the research, regularly eating almonds may increase the production of butyrate in the gut.

This short-chain fatty acid can help strengthen the gut lining and reduce inflammation.

Most people tolerate almonds well

Photo: Shutterstock.com

For the vast majority of people, almonds are a food that is generally well tolerated. The clear exception is individuals with nut allergies, who should avoid them.

They can be a better alternative to processed snacks

Photo: Shutterstock.com

Nutrition experts point out that replacing highly processed snacks with a handful of almonds can be a simple improvement to your diet. It may benefit both gut and heart health.

Sources: Real Simple, Nutrients, and Journal of Applied Microbiology.