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Scientists Reverse Aging in Mice with a Single Injection

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Aging is an unavoidable part of life, but what if it could be slowed—or even reversed? Researchers in China have made a breakthrough discovery that could change the way we understand aging.

In a new study, older mice regained lost fur, improved their physical abilities, and even lived longer after receiving an injection of a specific molecule.

Now, scientists are eager to explore whether this anti-aging effect could work in humans.

Can Aging Be Reversed?

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Aging is often linked to a decline in cellular function. As we grow older, our cells lose their ability to divide, triggering a cascade of issues, from weakened muscles and hair loss to inflammation and disease susceptibility.

Now, researchers believe they may have found a way to counteract this natural decline.

The Discovery That Turned Back Time

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In a groundbreaking experiment, Chinese scientists injected a molecule called miR-302b into aging mice. The results were astonishing: treated mice regrew lost fur, improved their grip strength, and performed better in physical tests compared to their untreated counterparts.

A Longer Life for Treated Mice

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Not only did the injection improve physical and cognitive function, but it also extended the mice’s lifespan.

On average, those treated with miR-302b lived 4.5 months longer than those that did not receive the injection.

The Role of MicroRNA in Aging

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MicroRNA molecules like miR-302b regulate gene expression, influencing everything from immune response to cellular repair.

Scientists believe this molecule may reactivate youthful cell behavior, effectively slowing down or even reversing signs of aging.

How Was the Treatment Delivered?

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To introduce miR-302b into the body, researchers packaged the molecule inside exosomes—tiny biological carriers that transport RNA between cells.

These exosomes were extracted from human stem cells, making them an effective tool for delivering the anti-aging compound.

The Study Focused on Elderly Mice

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The experiment, led by biophysicist Guangju Ji from the Chinese Academy of Sciences, involved mice aged 20 to 25 months—equivalent to humans in their 60s or 70s.

This ensured that the effects of the treatment were observed in subjects that had already shown signs of aging.

Improved Brain Function and Mobility

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Beyond physical changes, treated mice also performed better in cognitive tests. They completed a water maze challenge faster than untreated mice, suggesting an improvement in memory and spatial awareness.

Reduced Inflammation and Healthier Bodies

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One of the key benefits of the treatment was a marked reduction in inflammation, which is linked to age-related diseases such as Alzheimer’s, arthritis, and cardiovascular conditions.

What Does This Mean for Human Aging?

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While the study offers exciting possibilities, scientists caution that it is still too early to know whether miR-302b will have the same effect in humans.

More research is needed to determine if this technique can be safely and effectively applied beyond the laboratory.

A New Era in Anti-Aging Research

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If further studies confirm similar effects in humans, this discovery could redefine how we approach aging and age-related diseases.

From longer lifespans to improved quality of life, the potential impact of this research is enormous. The question remains: could a simple injection be the key to unlocking a healthier, longer future?

The article is based on information from Illustreret Videnskab.

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