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These Five Factors Are Behind One in Five Deaths Worldwide

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A massive international study reveals that just five lifestyle-related risks are responsible for half of all cardiovascular disease and 20% of all deaths. Here’s what you need to know—and what you can do.

High Blood Pressure

A clinician in the process” by Centers for Disease Control and Prevention/ CC0 1.0

The leading contributor to heart disease globally. Constantly elevated blood pressure stresses the heart and increases the risk of stroke and heart attack.

High Cholesterol

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Too much cholesterol can clog your arteries, restricting blood flow and raising the risk of serious heart conditions.

Type 2 Diabetes

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Diabetes harms blood vessels and can lead to inflammation throughout the body. It also significantly raises the risk of heart complications.

Obesity

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Excess weight, especially in midlife, amplifies the effects of other risk factors and places a heavy burden on the cardiovascular system.

Smoking

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Tobacco use damages arteries, limits oxygen delivery, and accelerates vascular aging—making it one of the deadliest preventable habits.

Women Are Disproportionately Affected

Senior women walking
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The study found that women, particularly in Europe, are more vulnerable to the combined impact of these five risk factors.

Heart Disease Is Largely Preventable

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Simple lifestyle changes—like eating well, staying active, quitting smoking, and managing blood pressure—can drastically cut your risk.

Regional Differences Matter

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Eastern Europe and Russia have even higher rates of cardiovascular disease linked to these five risks, showing the need for region-specific health campaigns.

Small Changes, Big Impact

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Even small shifts in daily behavior can protect against heart disease and premature death. It’s never too late to start.

Global Findings, Local Lessons

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Although the data spans 34 countries, the message is clear for everyone: take ownership of your health, because these risks are universal.

This article is based on information from Videnskab.dk

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