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Scientists find link between daily steps and reduced Alzheimer’s risk

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A 14-year study suggests that even a few thousand steps a day may slow the buildup of Alzheimer’s-related proteins and delay memory decline.

There’s something reassuring about small routines — a morning walk, taking the stairs, a stroll after dinner.

They don’t seem like much, but for your brain, they might make all the difference. A new long-term study from the United States suggests that these everyday movements could slow the silent progression of one of the world’s most devastating diseases: Alzheimer’s.

A 14-year look into the aging brain

At Massachusetts General Brigham Hospital in Boston, neuroscientist Wai-Ying Wendy Yau and her team followed nearly 300 participants between the ages of 50 and 90 for over a decade.

Every year, the volunteers underwent brain scans, memory tests, and physical activity tracking. None of them had cognitive decline at the start of the study.

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Over 14 years, the team observed that even light daily activity — the kind most people could easily fit into their routine — seemed to slow the buildup of proteins that damage the brain in Alzheimer’s.

These include amyloid-beta, which appears early in the disease, and tau, which is closely linked to memory loss and mental decline.

The surprising power of a few thousand steps

Participants who walked just 3,000–5,000 steps a day showed slower brain changes and milder cognitive decline compared with those who were less active.

For individuals with high amyloid levels — a major Alzheimer’s risk marker — that modest movement appeared to delay symptoms by about three years. At 5,000–7,500 steps a day, the progression slowed by as much as seven years.

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The results suggest that preventing Alzheimer’s doesn’t require intense workouts or dramatic lifestyle changes. Rather, consistent, low-effort movement could help protect brain health well into old age.

Why moving matters for memory

The researchers believe that regular physical activity boosts blood circulation to the brain, reduces inflammation, and increases levels of certain hormones and growth factors that support healthy neurons.

Together, these changes may help the brain clear out harmful proteins more efficiently and maintain stronger connections between brain cells.

To make it practical, the team encourages simple daily habits: walk during TV commercials, park a little farther away, or invite a friend for a walk instead of sitting down for coffee. Each small effort adds up — and for the brain, every step counts.

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A promising start, but more research ahead

While the findings are hopeful, Yau emphasizes that they show a correlation, not proof of cause and effect.

More controlled clinical trials are needed to confirm whether light activity truly slows tau buildup and cognitive decline.

Still, the message is clear: staying gently active could be one of the simplest ways to support brain health.

The full study was published in Nature Medicine and adds to growing evidence that movement — even in small doses — may be one of the most powerful tools we have to delay dementia.

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The article is based on information from Illustreret Videnskab and Nature

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