The CDC’s new fall vaccine rules: Who needs the stronger flu shot and when to go

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The guidance for this season draws a clearer line on who gets the stronger flu shot at 65 and over, and who still needs a COVID dose.

You probably know the fall feeling. A pharmacy sign in the window, a nagging note on the fridge, and no clear answer about whether to go this week or wait a few more weeks.

The CDC has now set out its interim recommendations for the 2026-2027 respiratory virus season.

Everyone 6 months and older should get an annual flu vaccine, and most people should aim for September or October.

Adults 65 and older are steered toward a stronger shot. The agency says this group should preferentially receive a high-dose, recombinant, or adjuvanted flu vaccine when one is available, rather than a standard formulation.

Also read: Protein found to explain why exercise works against type 2 diabetes

What is new for adults 65 and older

The three options work differently. High-dose shots contain more flu protein than a standard vaccine.

Adjuvanted shots include an added ingredient that boosts the immune response, which tends to slip with age.

Recombinant vaccines are made without eggs and also deliver a larger dose of flu protein. All three are built to work harder for an older immune system.

People with an egg allergy can still receive any age-appropriate flu vaccine, egg-based or not, the agency notes.

Also read: Working out with your partner may do more for your relationship than you expect

COVID shots recommended for all adults 18 and older

According to the CDC's routine COVID-19 vaccination guidance, a 2026-2027 COVID-19 vaccine is now recommended for all adults 18 and older.

The exact product and number of doses depend on age and vaccination history.

For children ages 6 months to 17 years with moderate or severe immunocompromise, the agency recommends vaccination.

Other children fall under shared clinical decision-making, meaning parents and a healthcare professional weigh the choice together.

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When healthcare workers can return after a respiratory illness

The agency has also simplified return-to-work rules for healthcare personnel with the flu, COVID-19, RSV, or another viral respiratory infection. All four conditions have to be met before going back.

According to AHCA/NCAL's summary of the updated CDC guidance, workers need at least three days from symptom onset, and 24 hours fever-free without fever-reducing medication.

Symptoms must be improving, and the person must feel well enough to work.

Testing is no longer part of the criteria. Returning staff should still wear a mask around patients, coworkers, and visitors through at least the end of day seven.

Also read: Small shifts in sleep, movement and food linked to a 10% drop in major heart events

People with ongoing symptoms, a weakened immune system, or questions about which flu shot fits them should talk with their doctor or pharmacist before booking.

The agency says vaccination should continue through the fall and winter while flu and COVID viruses are circulating.

Also read: A difficult pregnancy may raise your heart and kidney risk for years to come

This article is made and published by Mie Hermansen, who may have used AI in the preparation.

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