A new study suggests that a chemical found in your cookware, water, and even food packaging may be the reason some people suffer severe liver damage from alcohol — while others don’t. Here's what scientists have discovered.
PFOS is everywhere – and that’s the problem

PFOS is part of a group of synthetic compounds known as PFAS, or “forever chemicals,” because they accumulate in the body and the environment. They’re used in non-stick pans, water-resistant fabrics, and food wrappers.
Dangerous duo: Alcohol and PFOS

A new study from the University of Louisville shows that when PFOS combines with alcohol, liver damage becomes significantly worse — due to fat buildup, inflammation, and disrupted repair functions.
Why some heavy drinkers get sick — and others don’t

Only around one-third of people who drink heavily develop serious liver disease. Scientists now believe that environmental toxins like PFOS could be the missing link.
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This chemical disrupts how your liver processes fat

PFOS interferes with the liver’s ability to handle fat, causing fatty buildup — one of the earliest warning signs of liver disease.
Gene activity changes with dual exposure

The combination of alcohol and PFOS triggers harmful gene activity linked to oxidative stress, inflammation, and even pathways that may lead to cancer.
60% of PFOS ends up in your liver

The study found that more than half of PFOS exposure is stored in the liver — the same organ already under attack from alcohol.
Your liver's healing ability is weakened

The liver usually recovers well from alcohol-induced stress. But PFOS appears to push the damage further, reducing the organ’s natural resilience.
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You're probably exposed daily

From drinking water to fast food packaging, most people come into contact with PFOS regularly. In fact, 95% of Americans are believed to carry it in their blood.
Men and women may respond differently

Ongoing research is exploring whether biological sex influences how the liver reacts to combined exposure from alcohol and PFAS chemicals.
How to reduce your PFOS exposure

Swap non-stick pans for stainless steel or cast iron, use water filters, avoid stain-resistant coatings, and choose PFAS-free products whenever possible.
This article is based on information from the News Medical
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