Most people associate cancer with pain, weight loss, or fatigue. But some of the very first symptoms can appear in a completely different part of the body — the legs. Here’s what doctors and cancer specialists say you should pay attention to.
Sudden swelling in one leg
When blood stops flowing normally, a clot can form deep within the veins of the leg. Swelling — especially on just one side — can be an early warning sign that shouldn’t be ignored.
A throbbing or tight sensation
An unusual ache or pressure in the calf that isn’t related to exercise could indicate deep vein thrombosis, often one of the first physical reactions linked to pancreatic cancer.
Red or darker skin tone
Discoloration around the leg can reveal poor blood circulation. This irritation of the blood vessels is a common reaction and should always be checked by a doctor.
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Unusual warmth in the leg
If one leg feels warmer to the touch than the other — even when you haven’t been active — it could be a sign of inflammation caused by a blood clot. It’s a subtle but classic warning sign.
Unexplained pain
Pain in the calf or thigh that appears out of nowhere, without injury or strain, can be the body’s way of signaling that something more serious is happening internally.
Shortness of breath or chest tightness
When a clot travels from the leg to the lungs, it can cause a life-threatening condition called pulmonary embolism. It typically manifests as difficulty breathing, coughing, or sharp chest pain.
Fatigue and weakness
Pancreatic cancer often disrupts how the body produces and uses energy, leaving people feeling drained and weak — even after a full night’s rest.
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Dark urine and pale stools
When the cancer affects the bile ducts, bilirubin levels in the blood can rise. This causes urine to darken and stools to become lighter — a classic sign that something’s wrong.
Itchy skin without a rash
A buildup of bile salts in the bloodstream can trigger severe itching, often on the arms and legs. It’s an indirect but important signal that the liver or pancreas might be under stress.
Unexplained weight loss and loss of appetite
As the body fights the disease, it burns through energy faster than usual. That can lead to sudden weight loss and a reduced desire to eat — even without changing your diet.
Persistent abdominal or back pain
Although early signs may appear in the legs, pain in the stomach or lower back can indicate that the cancer has progressed. The tumor may press on nerves or nearby organs, causing lasting discomfort.
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This article is based on information from LADbible
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