People with type 2 diabetes have an increased risk of developing kidney disease.
Therefore, it is important to keep blood pressure under control, as high blood pressure can place additional strain on the kidneys, according to SciTechDaily.
Today, many patients are treated with RAS inhibitors and SGLT2 inhibitors, which researchers say may protect the kidneys and reduce the risk of kidney failure.
31,000 people studied
Researchers analyzed data from more than 31,000 adults with type 2 diabetes between 2016 and 2021.
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All participants received both RAS inhibitors and SGLT2 inhibitors.
Some patients were also prescribed blood pressure medication from the dihydropyridine calcium channel blocker group, also known as DCCBs.
The researchers compared this group with patients who used other types of blood pressure medication.
Participants were followed for approximately three and a half years, and the results were presented at the 63rd Congress of the European Renal Association.
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Worsening kidney function
The researchers suggest that DCCBs may affect blood flow in the kidneys’ small filtering units in a way that could increase stress on the kidneys.
According to the researchers, this may be a possible explanation for the findings.
The results showed that patients who used DCCBs in combination with the other treatments had a 33 percent higher risk of severe progression of kidney disease compared with patients who received other blood pressure medications.
The study cannot prove that the medication directly causes kidney damage.
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The researchers therefore emphasize that further studies are needed.
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