Chronic migraine means having headaches at least 15 days per month. Finding an effective treatment can often be difficult.
Researchers reviewed 43 studies involving adult migraine patients. They found that several older types of medication have uncertain effects, including topiramate, valproate, and propranolol.
Botox may also help some patients, but the researchers believe the treatment often causes more side effects.
Medication targets protein
The study, published in Annals of Internal Medicine, also focused on newer medications that target the CGRP protein.
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The protein plays a role in migraine attacks and contributes to pain and inflammation.
The medication is available in forms such as tablets, nasal sprays, and injections. According to the researchers, patients generally experienced fewer side effects compared with older treatments.
However, the researchers say more studies are still needed to examine the long-term effects of the medication.
Fewer migraine days
The most important finding of the study was that the newer treatments reduced the number of migraine days by an average of around two days per month.
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At the same time, the researchers stressed that the best treatment depends on each patient’s individual needs and financial situation.
Sources: HealthDay and Annals of Internal Medicine.
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